https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:123 Sat 24 Mar 2018 07:43:17 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22827 Sat 24 Mar 2018 07:16:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51247 0.2). Nonetheless, the mean expression level of FAT1 was significantly higher in leukemic patients (AML and ALL) than in normal CD34+ cells (p=0.029). Additionally, the FAT1 expression levels were significantly higher in both CD34+ and CD34-leukemic patients than in normal CD34+ cells (p=0.028). Conclusion: No significant differences were found between FAT1 expression in CD34+ and CD34-leukemic samples (p> 0.3). Thus, higher FAT1 expression was evident in ALL and AML leukemia cells but this appeared unrelated to CD34 expression. This suggests in a proportion of adult acute leukemia, FAT1 expression may prove to be a suitable target for therapeutic strategies.]]> Mon 28 Aug 2023 12:28:18 AEST ]]>